Actress Rosanna Arquette has raised serious questions regarding the death of Virginia Giuffre, a prominent figure in the Jeffrey Epstein sex trafficking case who died in April 2025. In an interview published Saturday, March 7, by London's The Times, Arquette stated unequivocally that she does not believe her friend died by suicide.
"I knew Virginia. I don't think she killed herself," Arquette, 66, told the publication. When asked directly whether she believed Giuffre died by suicide, the actress replied, "I do not."
Members of the Giuffre family announced in April 2025 that Virginia had died by suicide at age 41. The family statement described her as "a fierce warrior in the fight against sexual abuse and sex trafficking" who "was the light that lifted so many survivors." Giuffre was survived by three children: Christian, Noah, and Emily, whom she shared with estranged husband Robert Giuffre.
Arquette is not alone in questioning the circumstances surrounding Giuffre's death. Her father, Sky Roberts, called for an official inquiry in April 2025, pointing to previous social media posts in which his daughter stated she had no suicidal ideation. Virginia Giuffre's attorney, Karrie Louden, told The Sun in April 2025 that she had "big question marks" about how her client died.
"When I got the phone call, I was like, 'Are you joking?'" Louden recalled. "Because there was no sign that that was something she was considering."
Arquette explained her connection to Giuffre's case through her own experience with disgraced Hollywood producer Harvey Weinstein. The actress accused Weinstein of sexual misconduct at The Beverly Hilton in the 1990s, allegations he has denied. "I had many conversations with the Epstein women," Arquette told The Times. "Those women are warriors right now, and we need to protect them."
Virginia Giuffre became a central figure in the Jeffrey Epstein scandal after accusing Epstein and his former girlfriend Ghislaine Maxwell of sexually trafficking her to Andrew Mountbatten-Windsor, formerly known as Prince Andrew, three times, including when she was 17 years old in 2001. Mountbatten-Windsor denied the allegations in a 2019 Newsnight interview, stating he had "no recollection of ever meeting" Giuffre.
The former prince reached a private settlement with Giuffre in 2022 after she filed a sexual assault lawsuit against him. He made no admission of guilt as part of the settlement agreement.
Jeffrey Epstein died by suicide in August 2019 at age 66 following his arrest on federal sex trafficking charges. Ghislaine Maxwell, now 64, was sentenced to 20 years in prison in 2022 after being convicted on sex trafficking charges. Maxwell maintains her innocence and has requested clemency from President Donald Trump.
In February, Mountbatten-Windsor was arrested on suspicion of misconduct in a public office. He has been accused of sharing confidential information with Epstein while serving as a United Kingdom trade envoy from 2001 to 2011. Following the arrest, Giuffre's family members Sky and Amanda Roberts, along with Danny and Lanette Wilson, released a statement to NBC's Today on February 19.
"At last," the family stated. "Today our broken hearts have been lifted at the news that no one is above the law, not even royalty. On behalf of our sister, Virginia Roberts Giuffre, we extend our gratitude to the Thames Valley Police for the investigation and arrest of Andrew Mountbatten-Windsor."
The questions raised by Arquette, Giuffre's family, and her legal representative highlight ongoing concerns about the circumstances of her death and underscore the lasting impact of the Epstein trafficking case on survivors and their advocates.
If you or someone you know is a human trafficking victim, contact the National Human Trafficking Hotline at 1-888-373-7888. If you or someone you know is struggling or in crisis, help is available by calling or texting 988 or visiting 988lifeline.org.